Sometime in the near future, paraplegic prison inmate Matt Mills meets The Board of Satoshi-Telefair Industries, who thank him for joining the Program. Under pressure and with a promise to make him walk again, Mills agrees to volunteer. He is injected with a synthetic nanomaterial and suffocated, only to wake up with restored use of his legs, yet alone in a steel cell in the first spoke of an experimental apparatus - The Wheel. A series of assailants inflict a multitude of damage to Mills body and torment his mind, yet the synthetic nanomaterial not only restores his damaged organs, it re-engineers his strength. The experiment might be designed to kill, but Mills is determined to survive - and get back to his daughter before The Board finds her first.余男也称：;宁浩导演用尽了演员身上最有意思的那一部分，去体现他想要气质
近日，康斯坦丁电影公司宣布即将重启这一套著名的恐怖片伊丽莎白.萧和财团巨佬有素质区分么？都是为了活下往，无外乎一个自救，一个求救。
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